longevity

Pomegranate vs Urolithin A: Can You Get Enough From Food?

Pomegranate provides the precursors your gut can convert into Urolithin A—but conversion varies dramatically between people. Here’s how food-derived and direct Urolithin A exposure actually compare.

12 septembre 2026

Reviewed by the Celnovix Editorial Team
Last reviewed: September 2026

Pomegranate and Urolithin A are closely connected.

But they are not the same thing.

Pomegranate contains compounds that your gut microbiome can potentially transform into:

Urolithin A.

Direct Urolithin A supplements provide:

Urolithin A itself.

That difference matters because not everyone converts pomegranate compounds into Urolithin A equally well.

In one human study involving 100 healthy adults, approximately:

40%

became relatively high Urolithin A converters after drinking pomegranate juice.

The remaining approximately:

60%

were still either:

Poor converters
Non-converters

Direct supplementation with 500 mg of Urolithin A produced much more consistent systemic exposure across participants.

So the better question is not:

“Is pomegranate better than Urolithin A?”

It is:

“Do pomegranate and direct Urolithin A provide the same biological exposure?”

Current human research says:

No.

Pomegranate vs Urolithin A: Quick Comparison

Feature	Pomegranate	Direct Urolithin A
Contains Urolithin A directly in meaningful amounts	No	Yes
Contains ellagitannin precursors	Yes	Usually not the main purpose
Requires gut microbial conversion	Yes	Much less
UA production predictable	No	More predictable
Depends strongly on metabotype	Yes	Less for initial UA exposure
Provides fiber and other nutrients	Whole fruit: Yes	No
Provides other polyphenols	Yes	No
Standardized UA dose	No	Yes
Replaces whole-food nutrition	No	No

Both can have a place in a healthy diet.

But they should not be treated as equivalent sources of Urolithin A.

Does Pomegranate Contain Urolithin A?

This is one of the most common misconceptions.

Pomegranate primarily contains:

Punicalagins
Ellagitannins
Ellagic acid-related compounds

These compounds act as:

precursors.

Your intestinal microbiota can metabolize them into:

urolithins.

Urolithin A is therefore better understood as:

a gut microbiome-derived metabolite

rather than simply:

a compound naturally abundant in pomegranate juice.

The Pathway From Pomegranate to Urolithin A

The biological pathway looks approximately like this:

Pomegranate

↓

Ellagitannins / Punicalagins

↓

Ellagic Acid

↓

Gut Microbiome

↓

Intermediate Urolithins

↓

Urolithin A

This conversion depends heavily on:

which microorganisms live in your gut.

Why Doesn’t Everyone Get the Same Urolithin A From Pomegranate?

Because human gut microbiomes are different.

People differ in:

Microbial species
Microbial abundance
Microbial enzyme activity
Functional metabolic pathways

Researchers have therefore identified different:

urolithin metabotypes.

These include:

UM-A
UM-B
UM-0

For the detailed explanation:

⁠Why Can’t Everyone Produce Urolithin A? Gut Metabotypes Explained

What Is UM-A?

UM-A individuals primarily produce:

Urolithin A

after consuming ellagitannin-rich foods.

These individuals have a gut microbial ecosystem capable of performing the necessary metabolic transformations.

What Is UM-B?

UM-B individuals produce:

Urolithin A
Urolithin B
Isourolithin A

and potentially other related metabolites.

This represents a different microbial metabolic profile.

What Is UM-0?

UM-0 individuals produce:

little or no detectable urolithins

after consuming dietary precursors.

That means someone can eat:

Pomegranate
Walnuts
Berries

and still generate very little Urolithin A.

What Did the Human Pomegranate vs Urolithin A Study Test?

One particularly useful human study directly compared:

pomegranate juice

with:

direct Urolithin A supplementation.

The study included:

100 healthy adults.

Participants were randomized to receive:

Approximately 8 fl oz / 240 mL of 100% pomegranate juice

or:

A food product containing 500 mg Urolithin A

Researchers then measured circulating:

Urolithin A and its metabolites.

⁠View the study on PubMed

How Much Urolithin A Was Actually in the Pomegranate Juice?

This is an important detail.

The pomegranate juice itself contained:

no detectable Urolithin A.

Instead, the approximately 240 mL serving contained precursor compounds including roughly:

71 mg punicalagins
36 mg ellagic acid

The gut microbiome then had to convert these precursors into:

Urolithin A.

How Many People Produced Urolithin A From Pomegranate Juice?

Before the intervention:

only about 12%

of participants had detectable circulating Urolithin A glucuronide.

After drinking pomegranate juice:

At 6 Hours

Approximately:

28%

had detectable circulating UA glucuronide.

Only around:

were classified as high producers at that point.

At 24 Hours

Approximately:

40%

were classified as relatively high converters.

But about:

60%

still converted poorly or failed to convert the pomegranate precursors efficiently.

⁠View the full study

What Happened With Direct Urolithin A?

The same study gave participants:

500 mg direct Urolithin A.

This produced circulating Urolithin A metabolites:

much more consistently across the study population.

The authors reported substantially greater systemic exposure compared with pomegranate juice.

This is the fundamental difference between:

precursor intake

and:

direct metabolite intake.

Does That Mean Pomegranate “Doesn’t Work”?

No.

That would be the wrong conclusion.

Pomegranate is a nutrient-rich plant food containing:

Polyphenols
Potassium
Vitamin-related compounds
Other phytochemicals

Whole pomegranate also provides:

fiber.

Its value should not be reduced to whether it produces a particular amount of Urolithin A.

The narrower conclusion is:

Pomegranate does not provide predictable Urolithin A exposure across individuals.

Is Pomegranate Juice the Same as Whole Pomegranate?

No.

Whole pomegranate arils provide:

Fiber
Natural sugars
Polyphenols
Micronutrients

Pomegranate juice generally has:

Much less fiber
A more concentrated carbohydrate load per serving
Polyphenols and ellagitannin-related compounds

So nutritional comparisons should distinguish between:

whole fruit

and:

juice.

Can Pomegranate Juice Produce Urolithin A?

Yes—in some people.

The human study clearly demonstrated that drinking pomegranate juice increased Urolithin A production in:

some participants.

But the magnitude varied substantially.

Some were:

High converters

Others were:

Low converters

Others were:

Non-converters

Why Did Researchers Wait 24 Hours?

Urolithin A production is not an immediate process.

Dietary precursors must travel through the gastrointestinal tract before reaching microbial communities involved in:

ellagitannin metabolism.

Urolithins are produced mainly in the:

colon.

That means microbial conversion takes time.

Can You Feel Urolithin A Being Produced?

No reliable subjective sensation indicates:

Urolithin A production.

You cannot determine whether you are a high converter based on:

Energy
Digestion
Mood
Muscle sensation

Research classification requires measuring:

metabolites.

Does Eating More Pomegranate Produce More Urolithin A?

Not necessarily.

This is one of the most important points.

Suppose someone has limited microbial capacity to convert:

ellagic acid → Urolithin A.

Giving that person more precursor may not produce a proportional increase in UA.

The metabolic bottleneck may remain:

the microbiome.

Is There a Pomegranate-to-Urolithin A Conversion Formula?

No.

There is no reliable equation such as:

“One pomegranate = 250 mg Urolithin A.”

or:

“Two glasses of pomegranate juice = 500 mg Urolithin A.”

That is not how microbial metabolism works.

Why Can’t We Calculate a Simple Equivalent Dose?

Because conversion depends on:

Metabotype
Microbial abundance
Gut transit
Food composition
Precursor concentration
Individual metabolism

Even two people consuming the exact same drink may achieve:

very different circulating UA concentrations.

Is 500 mg Urolithin A Equal to a Certain Amount of Pomegranate?

No scientifically valid food-equivalence ratio has been established.

A 500 mg direct Urolithin A dose is:

500 mg of the downstream metabolite.

Pomegranate provides:

upstream precursors.

Those are fundamentally different exposures.

Could You Just Drink More Pomegranate Juice?

From a Urolithin A standpoint:

not reliably.

If you are a poor converter, drinking additional juice does not guarantee proportionally greater UA production.

It can, however, add:

Calories
Natural sugars

So “more juice” should not automatically be treated as a strategy for obtaining a standardized UA dose.

What About Pomegranate Extract?

Pomegranate extracts can contain concentrated:

Punicalagins
Ellagic acid
Ellagitannins

But they still generally depend on:

gut microbial conversion

to generate Urolithin A.

A concentrated precursor is still:

a precursor.

Does Pomegranate Extract Guarantee Urolithin A?

No.

Earlier human research using pomegranate extract found substantial interindividual variation.

In one study, some participants increased UA production after pomegranate extract.

Others remained:

non-producers.

⁠View the study on PubMed

What Did That Pomegranate Extract Study Find?

Twenty healthy participants consumed:

1,000 mg pomegranate extract daily

for:

four weeks.

Researchers observed three broad response patterns:

People who did not initially produce UA but began producing it during the intervention
Existing producers whose UA production increased
People who remained non-producers

This again demonstrates:

microbiome-dependent variability.

Can Repeated Pomegranate Intake Turn a Non-Producer Into a Producer?

Sometimes—but not reliably.

The four-week study showed that some participants who were initially non-producers developed detectable production.

But others remained:

non-producers even after repeated intake.

So repeated exposure may affect microbial metabolism in some individuals.

It does not guarantee conversion.

Does This Mean Your Metabotype Can Change?

Potentially.

The microbiome is dynamic.

It can change with:

Diet
Age
Antibiotics
Health status
Environment

But there is currently no validated protocol for reliably converting:

UM-0 → UM-A.

What About Walnuts Instead of Pomegranate?

Walnuts also contain:

ellagitannin-related precursors.

Gut bacteria can metabolize these compounds into:

urolithins.

But the same metabotype issue applies.

Walnuts do not guarantee standardized Urolithin A exposure either.

What About Berries?

Certain berries contain:

ellagic acid and ellagitannins.

Examples include:

Raspberries
Blackberries
Strawberries

Again:

precursor intake does not equal predictable UA production.

Are There Foods Naturally High in Urolithin A?

Urolithin A is not typically consumed from ordinary foods in the same way as:

Vitamin C
Protein
Creatine

It is mainly:

generated through microbial metabolism.

For a complete food guide:

⁠Foods Rich in Urolithin A: Natural Sources and What to Know

Pomegranate vs Direct Urolithin A: What Is the Main Difference?

The simplest distinction is:

Pomegranate

Provides:

raw materials.

Direct Urolithin A

Provides:

the final microbial metabolite.

That difference creates much more predictable systemic exposure with direct supplementation.

Is Direct Urolithin A More Bioavailable?

Human research suggests direct UA supplementation results in:

higher and more consistent circulating exposure

than relying on pomegranate precursor conversion.

In the 100-person comparison study, direct 500 mg Urolithin A produced substantially greater exposure than pomegranate juice.

But “more bioavailable” does not automatically mean:

better for every health outcome.

Higher Blood Levels Do Not Automatically Mean Better Health

This is an important YMYL distinction.

A study showing:

higher circulating Urolithin A

does not by itself prove:

Better longevity
Better disease prevention
Better cardiovascular outcomes
Longer lifespan

It proves:

more consistent exposure.

Clinical outcomes require separate research.

Is Direct Urolithin A Better for Mitophagy?

Direct Urolithin A has been used in human studies showing changes in:

Mitochondrial gene expression
Acylcarnitines
Mitochondrial-related proteins

This provides more standardized conditions for studying UA biology.

For the mechanism:

⁠Urolithin A and Mitophagy: How Does It Actually Work?

Does Pomegranate Activate Mitophagy?

It is not scientifically accurate to assume:

pomegranate = standardized mitophagy activation.

Pomegranate contains many bioactive compounds.

And whether it generates meaningful UA exposure depends on microbial conversion.

Any health effect of pomegranate could also involve:

other polyphenols and metabolites.

Can Pomegranate Support Healthy Aging?

Pomegranate can absolutely fit within a nutrient-dense dietary pattern.

But “healthy aging” is broad.

No single fruit should be positioned as:

Reversing aging
Preventing all age-related disease
Extending human lifespan

Whole dietary patterns matter much more.

Is Urolithin A a Replacement for Pomegranate?

No.

A supplement containing Urolithin A does not provide all of the:

Fiber
Micronutrients
Plant compounds

present in whole foods.

Direct UA answers a different question:

Can we provide standardized exposure to a specific microbial metabolite?

Should You Stop Eating Pomegranate if You Take Urolithin A?

There is no reason to frame the choice this way.

The two can play completely different roles.

Pomegranate

Can be part of:

a healthy dietary pattern.

Direct Urolithin A

Is used to provide:

standardized UA exposure

independent of microbial conversion ability.

Pomegranate Juice vs Urolithin A Supplement

Another useful comparison:

	Pomegranate Juice	Direct UA
Whole-food-derived beverage	Yes	No
UA present directly	No detectable UA in comparison trial	Yes
Requires microbiome	Yes	Much less
Exposure variability	High	Lower
Contains sugars	Yes	Depends on formulation
Contains other polyphenols	Yes	Depends on formulation
Standardized UA amount	No	Yes

Whole Pomegranate vs Urolithin A

Whole pomegranate has another major advantage compared with juice:

fiber.

Fiber is important for:

Gastrointestinal function
Satiety
Overall dietary quality

A Urolithin A supplement cannot replace those benefits.

So this should not become:

food vs supplement.

It is:

different tools for different purposes.

Is Natural Always Better?

“Natural” is not a sufficient scientific measure of:

Effectiveness
Safety
Bioavailability

A naturally occurring precursor may produce highly variable exposure.

A standardized downstream metabolite may produce more predictable exposure.

Neither characteristic alone determines:

clinical benefit.

Is Direct Urolithin A Synthetic?

Commercial UA can be manufactured and purified to deliver a standardized compound chemically corresponding to Urolithin A.

The important scientific question is not simply:

natural vs synthetic.

It is:

What compound reaches the body?
At what dose?
With what purity?
With what human evidence?

Can You Produce 500 mg of Urolithin A From Food?

Current human evidence does not support assuming that ordinary food intake will generate:

500 mg of systemic Urolithin A.

That number should not be translated directly into:

Pomegranates
Cups of berries
Grams of walnuts

because food provides precursors rather than a standardized downstream UA dose.

Why Supplement Studies Use Direct Urolithin A

Direct supplementation reduces variability created by:

gut conversion.

That helps researchers study:

Pharmacokinetics
Safety
Muscle outcomes
Mitochondrial biomarkers

under more standardized conditions.

This is methodologically useful.

Does Direct Supplementation Work in Non-Producers?

In terms of exposure:

yes, it bypasses the need to produce UA from dietary precursors.

The 100-person human study showed that direct supplementation produced more consistent circulating UA regardless of natural conversion ability.

But this does not automatically prove:

non-producers receive greater clinical benefit.

That remains a research question.

What If You Are Already a High Producer?

Direct supplementation can still provide standardized exposure.

But current evidence does not clearly establish whether naturally high producers:

Benefit less
Benefit equally
Benefit more

than low producers.

More stratified trials are needed.

Does Your Diet Still Matter if You Supplement Urolithin A?

Absolutely.

Urolithin A cannot replace:

Protein
Fiber
Fruits
Vegetables
Healthy fats
Minerals
Vitamins

A supplement is not a substitute for:

overall nutrition.

Pomegranate vs Urolithin A for Muscle Health

If the goal is specifically to examine:

Urolithin A-related muscle outcomes,

the relevant human muscle trials used:

direct Urolithin A supplementation.

They did not simply tell participants to:

drink more pomegranate juice.

Research has investigated outcomes involving:

Muscle endurance
Selected strength measures
Walking performance
Mitochondrial biomarkers

For the complete evidence:

⁠Urolithin A and Muscle Health: What Human Trials Actually Show

Does Pomegranate Build Muscle?

No.

Pomegranate should not be positioned as a direct muscle-building food.

Building and maintaining muscle depends much more strongly on:

Resistance training
Protein
Total energy intake
Recovery

Urolithin A vs Pomegranate for Mitochondrial Health

Direct Urolithin A studies provide more specific evidence about:

UA exposure and mitochondrial-related biomarkers.

Pomegranate research is biologically broader because the fruit contains:

many compounds besides UA precursors.

So these are different evidence bases.

How Long Does Direct Urolithin A Take to Work?

Human studies have reported:

Within Hours

Circulating UA metabolites following direct supplementation.

Around 4 Weeks

Mitochondrial-related biomarker changes.

Around 2–4 Months

Selected muscle-related outcomes.

For more:

⁠How Long Does Urolithin A Take to Work?

Can You Take Direct Urolithin A Every Day?

Daily supplementation has been used in human trials.

Common studied amounts include:

500 mg/day
1,000 mg/day

for several weeks to several months.

For the safety and duration discussion:

⁠Can You Take Urolithin A Every Day?

How Much Urolithin A Should You Take?

Clinical trials provide useful research ranges.

They do not establish one universal dose for every person.

For the complete dose discussion:

⁠Urolithin A Dosage Guide

Is Pomegranate Safer Than Urolithin A?

This is not an appropriate simple comparison.

Whole pomegranate is:

a food.

Direct Urolithin A is:

a concentrated metabolite used as a supplement ingredient.

Their:

Doses
Composition
Exposure
Intended use

are different.

People with specific medical conditions may also have reasons to consider:

Sugar intake
Potassium intake
Medication interactions
Supplement use

individually.

Should You Choose Pomegranate or Urolithin A?

That depends on your goal.

If Your Goal Is Overall Diet Quality

Choose nutrient-dense whole foods, including fruits.

Pomegranate can fit well.

If Your Goal Is Standardized Urolithin A Exposure

Direct Urolithin A provides a more predictable amount than relying on microbial conversion from food.

If Your Goal Is Healthy Aging

Do not reduce the strategy to either one.

The bigger priorities remain:

Physical activity
Resistance training
Adequate protein
Nutrient-dense food
Sleep
Cardiometabolic risk management

Can You Use Both?

They do not need to be mutually exclusive.

Eating a healthy diet containing:

Fruits
Nuts
Berries

can coexist with supplement use.

But combining them does not automatically produce:

synergistic health benefits.

That would require evidence.

The Most Important Difference

The most important difference is:

predictability.

Pomegranate provides:

precursors whose conversion depends on your microbiome.

Direct Urolithin A provides:

a defined amount of UA independent of whether you are a high, low or non-producer.

That is why direct supplementation has been useful in clinical research.

What the Human Evidence Actually Shows

A useful summary is:

Pomegranate Juice

Contains ellagitannin and ellagic-acid precursors
Does not necessarily contain measurable UA itself
Can lead to UA production
Response varies substantially between people
Around 40% of participants in one study became high converters after 24 hours

Direct 500 mg Urolithin A

Provides UA directly
Does not require the same precursor-conversion step
Produces substantially more consistent circulating exposure
Has been used directly in human clinical research

What the Evidence Does Not Show

Current evidence does not prove that:

Pomegranate is ineffective
Direct UA is nutritionally superior to whole fruit
Everyone needs Urolithin A supplements
High UA blood levels guarantee longevity
UM-0 is a disease
More UA is always better
Food-derived and supplemental UA have identical long-term health effects

The Bottom Line

Can you get Urolithin A from pomegranate?

Yes—but indirectly.

Pomegranate provides:

Ellagitannins
Punicalagins
Ellagic acid-related compounds

Your gut bacteria then determine how efficiently those compounds become:

Urolithin A.

And that conversion varies dramatically.

In a human study of 100 healthy adults, after approximately:

240 mL of pomegranate juice,

only about:

40%

were classified as relatively high Urolithin A converters after 24 hours.

The remaining approximately:

60%

were still:

Low converters
Non-converters

By contrast:

500 mg direct Urolithin A

produced substantially more consistent circulating exposure across participants.

So:

Pomegranate and direct Urolithin A are not equivalent ways of obtaining Urolithin A.

Pomegranate remains a valuable plant food.

Direct UA simply answers a different problem:

how to provide standardized Urolithin A exposure despite differences in gut microbiome metabolism.

The best way to think about the choice is:

food for overall nutrition

and:

standardized supplementation for a specific metabolite exposure

rather than assuming one must replace the other.

Frequently Asked Questions

Does pomegranate contain Urolithin A?

Pomegranate primarily contains ellagitannins and ellagic-acid-related precursors. Gut bacteria can convert these compounds into Urolithin A.

Can everyone make Urolithin A from pomegranate?

No. Urolithin production varies substantially according to gut microbiome composition and metabotype.

How much pomegranate do you need to get Urolithin A?

There is no reliable food-to-UA conversion formula because microbial conversion varies significantly between individuals.

Is one glass of pomegranate juice enough?

One study used approximately 240 mL of pomegranate juice. About 40% of participants became relatively high UA converters at 24 hours, while around 60% remained low or non-converters.

Is 500 mg Urolithin A equal to one pomegranate?

No. Pomegranate contains precursors, not a standardized 500 mg amount of Urolithin A.

Can you get 500 mg Urolithin A from food?

There is no evidence-based dietary conversion showing that ordinary food intake reliably produces the same exposure as 500 mg of direct Urolithin A.

Is pomegranate juice better than Urolithin A?

They serve different purposes. Pomegranate provides multiple plant nutrients and polyphenols, while direct Urolithin A provides standardized exposure to a specific metabolite.

Is whole pomegranate better than pomegranate juice?

Whole pomegranate provides fiber that juice largely lacks, making it nutritionally different from juice.

Can pomegranate extract increase Urolithin A?

It can in some people, but conversion remains microbiome dependent. Some individuals remain non-producers even after repeated intake.

Do walnuts produce Urolithin A?

Walnuts contain ellagitannin-related precursors that gut microbes can convert into urolithins.

Do berries contain Urolithin A?

Certain berries contain ellagitannin and ellagic-acid precursors rather than standardized amounts of Urolithin A itself.

Why is direct Urolithin A more predictable?

It bypasses much of the gut microbial conversion required to transform dietary precursors into UA.

Is direct Urolithin A better for non-producers?

It provides UA exposure regardless of natural producer status, but stronger evidence is still needed to determine whether non-producers gain greater clinical benefit.

Can you eat pomegranate while taking Urolithin A?

There is no general reason they must be mutually exclusive, although individual dietary and medical considerations may differ.

Related Celnovix Guides

References

Singh A, et al.

Direct Supplementation With Urolithin A Overcomes Limitations of Dietary Exposure and Gut Microbiome Variability in Healthy Adults to Achieve Consistent Levels Across the Population

This randomized human study included:

100 healthy adults.

Participants received either:

Approximately 240 mL of 100% pomegranate juice
500 mg direct Urolithin A

The pomegranate juice contained approximately:

71 mg punicalagins
36 mg ellagic acid

but no detectable Urolithin A itself.

After 24 hours, approximately 40% of participants were classified as high UA converters following pomegranate juice, while approximately 60% remained low converters or non-converters.

Direct Urolithin A produced substantially more consistent circulating exposure.

The study involved researchers affiliated with Amazentis, the developer of the commercial Urolithin A ingredient evaluated.

⁠View the study on PubMed

⁠View the full text on PubMed Central

Li Z, et al.

Pomegranate Extract Induces Ellagitannin Metabolite Formation and Changes Stool Microbiota in Healthy Volunteers

Twenty healthy participants consumed:

1,000 mg pomegranate extract daily for four weeks.

Researchers observed three response patterns:

Newly induced Urolithin A producers
Existing producers with increased production
Persistent non-producers

The study demonstrates that repeated dietary precursor exposure does not guarantee UA production in everyone.

⁠View the study on PubMed

Tomás-Barberán FA, et al.

The Gut Microbiota Metabolism of Pomegranate or Walnut Ellagitannins Yields Urolithin Metabotypes That Correlate With Cardiometabolic Risk Biomarkers

This human research characterized:

UM-A
UM-B
UM-0

after consumption of ellagitannin-containing foods including:

Pomegranate
Walnuts

The work helped establish urolithin metabotypes as functional patterns of gut microbial metabolism.

Associations with cardiometabolic biomarkers were exploratory and should not be interpreted as proof that one metabotype causes better or worse health.

⁠View the study on PubMed

Evidence Transparency

Important limitations include:

The major direct pomegranate-vs-UA comparison was relatively small.
The direct UA intervention was industry associated.
Exposure data do not automatically prove clinical superiority.
Pomegranate contains many compounds beyond Urolithin A precursors.
Whole fruit differs nutritionally from juice.
Urolithin production varies by population and microbiome.
Metabotype can potentially change over time.
Clinical benefits according to producer status remain incompletely understood.
Standardized UA exposure should not be confused with guaranteed health benefit.

Editorial Standards

Celnovix distinguishes between:

Dietary ellagitannin intake
Ellagic-acid exposure
Gut microbial conversion
Circulating Urolithin A
Biological target engagement
Clinical outcomes

These are not interchangeable.

We do not interpret:

Pomegranate intake as a standardized UA dose
Higher UA exposure as automatic proof of better health
UM-0 as a disease
Direct supplementation as a replacement for fruit
One pharmacokinetic study as proof of long-term superiority

Medical Disclaimer

This article is provided for general educational and informational purposes only and does not constitute medical advice, diagnosis, treatment or individualized dietary or supplement guidance.

Pomegranate and Urolithin A should not be used as substitutes for appropriate medical treatment.

If you have diabetes, kidney disease, significant gastrointestinal disease, take prescription medications, are pregnant or breastfeeding, or have other medical concerns, discuss major dietary or supplement changes with an appropriately qualified healthcare professional.

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